Features of Lowe syndrome include:
- congenital (present at birth) glaucoma
- opacity of the cornea, the transparent covering of the iris and pupil, due to overgrowth of scar tissue in about half of affected people
- renal tubular dysfunction, which may lead to kidney failure
- learning disability ranging from mild to severe
- behavioural problems
- seizures, affecting about half of the children diagnosed with the syndrome (see entry Epilepsy).