Floating-Harbor syndrome is a rare genetic condition caused by
faults in a gene known as SRCAP. Those affected may be short in
stature, have delayed bone growth, delay in expressive language and
distinct facial features - prominent nose, deep-set eyes and a
long, thin upper lip. The ears may be low set and tipped backwards.
They may also have learning disability and dental anomalies as well
disease. In addition, there may be problems with the
development of teeth.
Diagnosis is made on the basis of the typical features including
facial features. Management of the condition includes extra support
with developmental and education programmes and regular orthodontic
(dental) care. Growth hormone therapy may be of benefit in some
patients to increase their growth and therefore height. All
cases are sporadic (with no family history). Affected families
should be referred to a genetics centre for information and
This overview is intended to be a basic description of the
condition. It is not intended to replace specialist medical advice.
We advise that you discuss your child's case with a qualified
medical professional who will be able to give you more detailed