Patients with Hashimoto's encephalitis often present with a depression of brain function (meaning that function is reduced), drowsiness and sometimes coma. Two types of Hashimoto's encephalitis have been described:
- the relapsing and remitting type (where symptoms at times worse and other times better) - which manifests with encephalopathy (a change in function or structure of the brain) and 'stroke-like' episodes
- the diffuse progressive (widely dispersed) type - which has a slow onset and a progressive course with occasional fluctuations and manifests with psychiatric symptoms, such as confusion, disorientation and psychosis.
Either of these may present with tremors, jerks or epileptic seizures.