The most common presenting symptom of I/HPAH is breathlessness (dyspnea) and this is often associated with tiredness. Dizziness and fainting spells (syncope) are also typical early symptoms. Individuals may experience chest pain, palpitation (a feeling of rapid heartbeats in the chest) and a dry cough. The range and severity of symptoms varies between individuals and can occur at rest, whilst walking or during periods of mild exercise. In the more advanced stages, an individual is able to perform only minimal activity and has symptoms even when resting. Ankle or abdominal swelling may occur. In general, the more severe the symptoms, the more advanced the disease.
Pulmonary hypertension may be associated with other conditions such as pulmonary embolism (blood clots in the lungs)lung disease and heart disease.Pulmonary arterial hypertension may be associated with drugs and toxins (typically the anorexigens which are drugs used to cause weight loss in the past), some types of congenital heart disease, autoimmune disorders, portal hypertension, HIV and schistosomiasis (an infection caused by a parasitic worm).